Education 1991-1997 University Marburg, Germany, Study of Psychology 2002 Doctorate in Human Biology 2004 Certificate Biometrics in Medicine 2008 Habilitation in Medical Biometry and Epidemiology
Professional Experience 1998-2001 Scientific employee at the Institute of Medical Biometry and Epidemiology, University Marburg, Germany 2001-2010 Scientific employee at the Institute of Medical Biometry and Statistics (IMBS), University Lübeck, Germany 2002–2010 Head elect of the working group Human Genetics of the German Society for Medical Informatics, Biometrics and Epidemiology (gmds) 2003–2009 Member of the Membership Committee of the International Genetic Epidemiology Society (IGES) (head 2008) 2006–2014 Member elect of the Fachausschuss Biometrie of the gmds 2010-2019 University Professor (W2) for Medical Biometry and Statistics, University Lübeck, Germany 2014-2016 Member elect of the Board of Directors of the IGES 2017/2018/2019 President-elect/President/Past president of the IGES since 2019 University Professor (W3) for Medical Biometry and Statistics and Director of the IMBS, University Lübeck, Germany
Prof. König gathered experience in biostatistics for clinical trials as well as in clinical and genetic epidemiology and machine learning. Participating in numerous national and international collaborations in leading roles, she has specific interests in predictive modelling also using large-scale data, biomarker-based trials, and novel study designs in clinical trials.
Biostatistics for clinical trials, including randomized controlled interventional trials, prognostic studies, biomarker-based clinical trials, and trials on digital health applications. Machine learning, prognostic and predictive modelling. Biostatistical education at all expertise levels.
Thiele H, […], König IR, Vonthein R, Rückert Y, Funkat A-K, Waha-Thiele Sd, Desch S, on behalf of the SOLVE-TAVI Investigators (2020) Comparison of newer generation self-expandable vs. balloon-expandable valves in transcatheter aortic valve implantation: the randomized SOLVE-TAVI trial. Eur Heart J 41:1890-9
Gola D, […], König IR (2020) Population bias in polygenic risk prediction models for coronary artery disease. Circ Genom Precis Med in press
De Marchis GM, Dankowski T, König IR, […], Katan M (2019) A novel, biomarkerbased prognostic score in acute ischemic stroke: the CoRisk score. Neurology 92:e1517-e25
Borsche M, König* IR, […], Klein C (2020) Mitochondrial damage-associated inflammation highlights Parkinson’s disease biomarkers in carriers of Parkin and PINK1 mutations Brain in press
König IR, […], Kopp M (2017) What is Precision Medicine? Eur Respir J 50:1700391
Principal investigator/responsible biostatistician in the German Center for Cardiovascular Research (DZHK, funded by BMBF), German Cen- ter for Lung Research (DZL, funded by BMBF), German Neonatal Network, Research Unit funded by the German Research Foundation DFG (Reduced Penetrance in Hereditary Movement Disorders) and Clinical Research Unit funded by the DFG (Pemphigoid diseases); Member of the Cluster of Excellence Inflammation at Interfaces/Precision Medicine in Chronic Inflammation.